Classics in spectroscopy isolation and structure elucidation of natural products pdf

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• Classics in Spectroscopy: Isolation and Structure Elucidation of Natural Products
• Classics in Spectroscopy: Isolation and Structure Elucidation of Natural Products
• Elements of natural products chemistry

It was written by the following authors: Dieter Sicker , Stefan Berger.

Classics in Spectroscopy: Isolation and Structure Elucidation of Natural Products

Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page. Pentahydroxyscirpene, a novel trichothecene-type compound, was isolated from Fusarium -inoculated rice. The structure of pentahydroxyscirpene was elucidated by 1D and 2D NMR spectroscopy and X-ray single-crystal diffraction. The conformation in solution was determined by NOESY experiments supported by quantum chemical calculations. In vitro toxicity tests showed that pentahydroxyscirpene inhibits protein synthesis as do other trichothecenes. Trichothecenes, a major class of mycotoxins, are among the most prominent fungal secondary metabolites harmful to human and animal health, causing a range of acute and chronic symptoms.

Classics in Spectroscopy: Isolation and Structure Elucidation of Natural Products

Natural products containing the tetramic acid core scaffold have been isolated from an assortment of terrestrial and marine species and often display wide ranging and potent biological activities including antibacterial, antiviral and antitumoral activities. Owing to their intriguing structure and biological activity, tetramic acid-containing agents, both natural and synthetic, are attracting increasingly significant attention from biologists and chemists. Indeed, this increasing enthusiasm has led to significant advances. The goal of this review is to present not only these advances but also the broader context that frames them and provides a complete view of the naturally occurring tetramic acids inclusive of studies aimed at isolation, structure elucidation, and evaluation of biological activities. Consistent with advances over the past decade this review covers the period spanning to

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Elements of natural products chemistry

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